American researchers have succeeded in the genetic defect in PSSM, a specific form of the cross crate to educate a significant step further. PSSM is a glycogen storage disease of muscle cells. Like now, it was found the gene for the enzyme "glycogen synthase" in affected horses is mutated in a way that the enzyme is more active than normal. The gene defect is dominantly inherited. This means that horses are more prone even with a copy of the mutated gene for storage myopathy and pass on the disease with 50% probability. If a horse from both parents a defective gene inherited, there is a defect with 100% probability further. On a genetic test to identify carriers of the mutated gene is in progress. This is of major importance for breeding, as all horses do not get with a mutated gene also Kreuzverschläge, but inherit the disease further.
Further information on storage myopathy in EquiVetInfo
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